Condensed tannins. 5. The oxidative condensation of (+)-catechin

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Regioselective Synthesis of Procyanidin B6, A 4-6-Condensed (+)-Catechin Dimer, by Intramolecular Condensation.

Proanthocyanidins, also known as condensed tannins or oligomeric flavonoids, are found in many edible plants and exhibit interesting biological activities. Herein, we report a new, simple method for the stereoselective synthesis of procyanidin B6, a (+)-catechin-(4-6)-(+)-catechin dimer, by Lewis acid-catalyzed intramolecular condensation. The 5-O-t-butyldimethylsilyl (TBDMS) group of 5,7,3'4'-...

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Condensed tannins. 20. Chromophoric properties of flavan-4-ols, flavan-3,4-diols and condensed tannins.

Brown, B. R. & MacBride, J. A. H. (1963). Chem. & Ind. p. 1037. Clark-Lewis, J. W. & Jackman, L. M. (1961). Proc. chem. Soc. p. 165. Clark-Lewis, J. W., Jackman, L. M. & Williams, L. R. (1962). J. chem. Soc. p. 3858. Clark-Lewis, J. W. & Katekar, G. F. (1962). J. chem. Soc. p. 4502. Clark-Lewis, J. W. & Mortimer, P. I. (1960). J. chem. Soc. p. 4106. Conroy, H. (1960). Advanc. org. Chem. 2, 308....

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CONDENSED TANNINS: THE FORMATION OF A DIARYLPROP ANOL-CATECHINIC ACm DIMER FROM BASE-CATALYZED REACTIONS OF (+ )-CATECHIN

Reaction of (+ )-catechin at pH 12 and 40 DC results in the stereoselective (if not stereospecific) formation of an enolic form of 1-[6-(3',4'-dihydroxyphenyl)7 -hydroxybicyclo[3.3.1 Jnonane-2,4,9-trione-3-ylJ -1-(3,4-dihyroxyphenyl )-3-(2,4,6-trihydroxyphenyl)-propan-2-ol. The n.m.r. chemical shift assignments determined by a variety of two-dimensional experiments permit a conclusion that the ...

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Increasing the oxidative stress response allows Escherichia coli to overcome inhibitory effects of condensed tannins.

Tannins are plant-derived polyphenols with antimicrobial effects. The mechanism of tannin toxicity towards Escherichia coli was determined by using an extract from Acacia mearnsii (Black wattle) as a source of condensed tannins (proanthocyanidins). E. coli growth was inhibited by tannins only when tannins were exposed to oxygen. Tannins auto-oxidize, and substantial hydrogen peroxide was genera...

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Interactions of Condensed Tannins with Selected Proteins

The relative affinities ufeondensed tannins purilied from sorghum, pinto bean, quebracho and wattle for six dissimilar protins have been determined by a competitive binding assay. The results indicate that tannin/protein interactions may be specific for different tanains as well as for different proteins. The highly specific interactions suggest that the differences in affinity are functionally...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1960

ISSN: 0306-3283

DOI: 10.1042/bj0760023